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Monday, July 6, 2020 | History

5 edition of A highly macroporous biodegradable composite scaffold for bone tissue engineering applications found in the catalog.

A highly macroporous biodegradable composite scaffold for bone tissue engineering applications

Limin Guan

A highly macroporous biodegradable composite scaffold for bone tissue engineering applications

by Limin Guan

  • 109 Want to read
  • 36 Currently reading

Published by National Library of Canada in Ottawa .
Written in English


Edition Notes

SeriesCanadian theses = -- Thèses canadiennes
The Physical Object
FormatMicroform
Pagination2 microfiches : negative.
ID Numbers
Open LibraryOL21137040M
ISBN 100612841332
OCLC/WorldCa57001575

1. Introduction. One of the most attractive subjects in tissue engineering is the development of a scaffold, a three-dimensional porous solid structure that plays a key role in assisting tissue regeneration [].Ideally, a scaffold must be porous, bioactive, and biodegradable and possess adequate mechanical properties suited to the biological by:   3D biodegradable scaffolds of polycaprolactone with silicate-containing hydroxyapatite microparticles for bone tissue engineering: high-resolution tomography and Cited by:

  Work on the development of highly porous biodegradable materials for orthopaedic tissue engineering has been supported by the U.S. National Institutes of Health (RAR, RDE and RAR). Modification of implantable scaffolds with magnesium and zinc for improvement of bone regeneration is a growing trend in the engineering of biomaterials. The aim of this study was to synthesize nano-hydroxyapatite substituted with magnesium (Mg2+) (HA-Mg) and zinc (Zn2+) (HA-Zn) ions in order to fabricate chitosan-agarose-hydroxyapatite (HA) scaffolds (chit/aga/HA) with improved by: 1.

  Bone tissue engineering is a rapidly developing area. Engineering bone typically uses an artificial extracellular matrix (scaffold), osteoblasts or cells that can become osteoblasts, and regulating factors that promote cell attachment, differentiation, and mineralized bone formation. Among them, highly porous scaffolds play a critical role in cell seeding, proliferation, and new 3D-tissue Cited by: Biodegradability falls in line with adequate mechanical properties of the scaffold. Following implantation, the scaffold must degrade in a timely manner to ensure proper remodeling of the tissue. Highly porous scaffolds are critical for cell infiltration especially when it comes to thick scaffolds where diffusion becomes a by:


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A highly macroporous biodegradable composite scaffold for bone tissue engineering applications by Limin Guan Download PDF EPUB FB2

Abstract A unique composite scaffold for bone‐tissue engineering applications has been prepared by combining biodegradable poly Preparation and characterization of a highly macroporous biodegradable composite tissue engineering scaffold Cited by: This book addresses the principles, methods and applications of biodegradable polymer based scaffolds for bone tissue engineering.

The general principle of bone tissue engineering is reviewed and the traditional and novel scaffolding materials, their properties and scaffold Cited by:   A unique composite scaffold for bone-tissue engineering applications has been prepared by combining biodegradable poly(lactide-co-glycolide) (PLGA) with bioresorbable calcium phosphate (CaP) cement particles through the process of particle fusion and phase separation/particle by: Our findings provide new insight into the development of degradable macroporous composite materials with “three-dimensional” surface microstructures as bone substitutes or tissue engineering scaffolds with potential for clinical by: 6.

A unique composite scaffold for bone-tissue engineering applications has been prepared by combining biodegradable poly(lactide-co-glycolide) (PLGA) with bioresorbable calcium phosphate (CaP) cement.

This study aimed to develop a practical three‐dimensional (3D) macroporous scaffold from aligned electrospun nanofibrous yarns for bone tissue engineering. A novel 3D unwoven macroporous nanofibrous (MNF) scaffold was manufactured with electrospun poly(L ‐lactic acid) and polycaprolactone (w/w ) nanofibers through sequential yarns Cited by:   The development of synthetic materials and their use in tissue engineering applications hasattracted much attention in recent years as an option for trabecular bone grafting.

Bioabsorbablepolyesters of the poly(α-hydroxy acids) family, and specifically polylactic acid (PLA), are wellknown bioabsorbable materials and are currently used for Cited by: For successful bone tissue engineering, a scaffold needs to be osteoconductive, porous, and biodegradable, thus able to support attachment and proliferation of bone cells and guide bone.

() demonstrated a practical 3D macroporous nanofibrous (MNF) scaffold obtained from aligned electrospun nanofibrous yarns for bone tissue engineering.

Human embryonic stem cell‐derived mesenchymal stem cells (hESC‐MSCs) were well attached on the 3D MNF scaffolds and the cells changed their original rounded shape to elongated and Cited by: Novel biodegradable threedimensional macroporous scaffold using aligned electrospun nanofibrous yarns for bone tissue engineering.

J Biomed Mater Res Part A Cited by: Biodegradable Polymer Scaffold for Tissue Engineering Article (PDF Available) in Trends in Biomaterials and Artificial Organs 25(1) January with 1, Reads How we measure 'reads'. The unique strength and resistance to mechanical compression of silk fibroin materials, the biocompatibility,, the slow rate of degradation, the utility of this protein in various forms for tissue engineering soft, and hard, tissue, as well as the longstanding use silk fibroin in suture applications suggest this biomaterial as a suitable substrate for tissue by: Ceramics have been widely used in the tissue engineering and regeneration fields.

43 This is not surprising as perhaps the most commonly treated tissue in such applications is bone, and ceramics can easily be formulated to have similar geometry, structure and, to some extent, physical and mechanical properties to native bone, such as the inorganic component, as well as having Cited by: 4.

BIODEGRADABLE POLYMER-BIOCERAMIC COMPOSITE SCAFFOLDS FOR BONE TISSUE ENGINEERING A. Boccaccini, X. Chatzistavrou, D. Mohamad Yunos, V. Califano1) *) Department of Materials, Imperial College London, London SW7 2BP, UK [email protected] 1) Dip.

Scienze Fisiche, Università degli Studi di Napoli “Fedrico II”, TeccFile Size: KB. Biodegradable macroporous scaffold with nano-crystal surface microstructure for highly effective osteogenesis and vascularization Article (PDF Available) in Journal of Materials Chemistry B 6( bone tissue engineering applications with a pore size and We have developed a biodegradable composite scaffold for bone the scaffold exhibits a highly inter-connected macroporous structure.

The process has been successfully used to fabricate polymer, ceramic, metal and composite scaffolds for bone tissue engineering [2–4] Laser engineered net shaping (LENS ™) a layer by layer SFF process that uses a high power laser (between W and 2 KW) to melt metal powders to form three dimensional structures based on CAD by: Biodegradable macroporous scaffold with nano-crystal surface microstructure for highly effective osteogenesis and vascularization the development of degradable macroporous composite materials with “three-dimensional” surface microstructures as bone substitutes or tissue engineering scaffolds with potential for clinical applications Cited by: 6.

A low flexural stiffness is one of the most important features in the design of a biodegradable scaffold for heart valve tissue engineering.

Altering the electrospinning parameters can modulate the microstructure and mechanical properties of the biodegradable polyurethane fibrous scaffold.

The design and functionalization of porous materials have been actively pursued to enable new material properties and applications 1,2, particular, the development of synthetic 3D macroporous Cited by:. Abstract Biodegradable polymers and bioactive ceramics are being combined in a variety of composite materials for tissue engineering scaffolds.

Materials and fabrication routes for three-dimensional (3D) scaffolds with interconnected high porosities suitable for bone tissue engineering Cited by: The biodegradable polymer/bioceramic composite scaffolds fabricated by this novel GF/PL method could enhance the bone regeneration efficacy of osteogenic cell transplantation for the treatment of bone defects, as compared with conventional composite by: Polymers, an international, peer-reviewed Open Access journal.

Dear Colleagues, I have been asked by the Editor of Polymers (MDPI) to be the Guest Editor of a Special Issue titled “Biodegradable polymer scaffolds for tissue engineering”.

This Special Issue is motivated by the still growing interest in the applications of biodegradable polymer scaffolds in the field of tissue engineering.